Varaico: Literature-Extracted Genetic Variants

Gene:KCNH2
Variant:p.T174T
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KCNH2

NM_000238.4:p.T174T

Associated Papers

High-throughput screens identify genotype-specific therapeutics for channelopathies.

Egly CL et al.

Jci Insight, 2025

41026531 (PubMed )
Supplement: jciinsight-10-191697-s190.xlsx › Figure_6B

Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.

Gardner A et al.

Molecular Pharmacology, 2017

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

Perry MD et al.

The Journal of General Physiology, 2013

23980196 (PubMed )
Supplement: supp_jgp.201310975_JGP_201310975_sm.pdf

Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.

Durdagi S et al.

The Journal of Pharmacology and Experimental Therapeutics, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."