Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ10
Variant:p.K67M
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KCNJ10

NM_002241.5:p.K67M

Associated Papers

Intracellular pH regulates the strength of the intrinsic inward rectification of Kir4.1/Kir5.1 channels.

Aréchiga-Figueroa IA et al.

Pflugers Archiv : European Journal of Physiology, 2025

H bonding at the helix-bundle crossing controls gating in Kir potassium channels.

Rapedius M et al.

Neuron, 2007

Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels.

Xu H et al.

American Journal of Physiology. Cell Physiology, 2000

Biophysical and molecular mechanisms underlying the modulation of heteromeric Kir4.1-Kir5.1 channels by CO2 and pH.

Yang Z et al.

The Journal of General Physiology, 2000

Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing.

Rapedius M et al.

Channels (austin, Tex.), 0

Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels.

Paynter JJ et al.

Channels (austin, Tex.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."