Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ11
Variant:p.R314C
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KCNJ11

NM_000525.4:p.R314C

Associated Papers

Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors.

Roberts JA et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2007

Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2).

Ribalet B et al.

Journal of Molecular and Cellular Cardiology, 2005

Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.

Lin YW et al.

The Journal of General Physiology, 2003

Molecular basis for Kir6.2 channel inhibition by adenine nucleotides.

Ribalet B et al.

Biophysical Journal, 2003

Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: interactions between SUR1 and positively charged domains on Kir6.2.

John SA et al.

The Journal of General Physiology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."