Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ11
Variant:p.L56M
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KCNJ11

NM_000525.4:p.L56M

Associated Papers

Effects of ZD0947, a novel and potent ATP-sensitive K+ channel opener, on smooth muscle-type ATP-sensitive K+ channels.

Mori K et al.

European Journal of Pharmacology, 2016

Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channels.

Li JB et al.

The Journal of Biological Chemistry, 2013

Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels.

Ponce-Balbuena D et al.

Molecular Pharmacology, 2012

Carvedilol inhibits Kir2.3 channels by interference with PIP₂-channel interaction.

Ferrer T et al.

European Journal of Pharmacology, 2011

ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2.

Ribalet B et al.

The Journal of Physiology, 2006

Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.

Kikuta J et al.

European Journal of Pharmacology, 2006

Critical protein domains and amino acid residues for gating the KIR6.2 channel by intracellular ATP.

Wu J et al.

Journal of Cellular Physiology, 2004

Requirement of multiple protein domains and residues for gating K(ATP) channels by intracellular pH.

Piao H et al.

The Journal of Biological Chemistry, 2001

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.

Trapp S et al.

The Journal of General Physiology, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."