Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ12
Variant:p.I223L
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KCNJ12

NM_021012.5:p.I223L

Associated Papers

Structural Basis for Differences in Dynamics Induced by Leu Versus Ile Residues in the CD Loop of Kir Channels.

Lü S et al.

Molecular Neurobiology, 2016

Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).

Rosenhouse-Dantsker A et al.

The Journal of Biological Chemistry, 2012

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.

Hansen SB et al.

Nature, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."