Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.F47F
Back to variants list

KCNJ2

NM_000891.3:p.F47F

Associated Papers

Determinants of trafficking, conduction, and disease within a K+ channel revealed through multiparametric deep mutational scanning.

Coyote-Maestas W et al.

Elife, 2022

35639599 (PubMed )
Supplement: elife-76903-data1.zip › SourceData › figure_output › Fig6.pdf

Ser165 in the second transmembrane region of the Kir2.1 channel determines its susceptibility to blockade by intracellular Mg2+.

Fujiwara Y et al.

The Journal of General Physiology, 2002

Residues beyond the selectivity filter of the K+ channel kir2.1 regulate permeation and block by external Rb+ and Cs+.

Thompson GA et al.

The Journal of Physiology, 2000

Probing pore topology and conformational changes of Kir2.1 potassium channels by cysteine scanning mutagenesis.

Kubo Y et al.

Febs Letters, 1998

The selectivity filter of a potassium channel, murine kir2.1, investigated using scanning cysteine mutagenesis.

Dart C et al.

The Journal of Physiology, 1998

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."