Associated Papers
From Crosstalk to Synergism: The Combined Effect of Cholesterol and PI(4,5)P2 on Inwardly Rectifying Potassium Channels.
Bukiya AN et al.
Advances in Experimental Medicine and Biology, 2023
Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).
Rosenhouse-Dantsker A et al.
The Journal of Biological Chemistry, 2012
Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore.
Rosenhouse-Dantsker A et al.
Biophysical Journal, 2011
Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini.
Rosenhouse-Dantsker A et al.
Channels (austin, Tex.), 0
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