Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.N60H
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KCNJ2

NM_000891.3:p.N60H

Associated Papers

The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.

Huang CW et al.

Pflugers Archiv : European Journal of Physiology, 2014

Carvedilol inhibits Kir2.3 channels by interference with PIP₂-channel interaction.

Ferrer T et al.

European Journal of Pharmacology, 2011

Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.

Kikuta J et al.

European Journal of Pharmacology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."