Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.M84K
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KCNJ2

NM_000891.3:p.M84K

Associated Papers

H bonding at the helix-bundle crossing controls gating in Kir potassium channels.

Rapedius M et al.

Neuron, 2007

Determinant role of membrane helices in K ATP channel gating.

Wang R et al.

The Journal of Membrane Biology, 2005

Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation.

Flagg TP et al.

The Journal of Physiology, 2002

Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH.

Fakler B et al.

The Embo Journal, 1996

Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels.

Paynter JJ et al.

Channels (austin, Tex.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."