Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.E125Q
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KCNJ2

NM_000891.3:p.E125Q

Associated Papers

Magnesium Ions as Modulators of Voltage-Gated and Ligand-Gated Ion Channels in Central Neurons.

Spasic S et al.

International Journal of Molecular Sciences, 2025

Negatively charged residues located near the external entrance are required for the Kir2.1 channel to function.

Hayashi M et al.

Pflugers Archiv : European Journal of Physiology, 2007

Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.

Fujiwara Y et al.

The Journal of General Physiology, 2006

Identification of a site involved in the block by extracellular Mg(2+) and Ba(2+) as well as permeation of K(+) in the Kir2.1 K(+) channel.

Murata Y et al.

The Journal of Physiology, 2002

Identification and molecular localization of a pH-sensing domain for the inward rectifier potassium channel HIR.

Coulter KL et al.

Neuron, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."