Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.S165L
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KCNJ2

NM_000891.3:p.S165L

Associated Papers

Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.

Huang CW et al.

Pflugers Archiv : European Journal of Physiology, 2015

Driving force-dependent block by internal Ba(2+) on the Kir2.1 channel: Mechanistic insight into inward rectification.

Hsieh CP et al.

Biophysical Chemistry, 2015

The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.

Huang CW et al.

Pflugers Archiv : European Journal of Physiology, 2014

Multiple residues in the p-region and m2 of murine kir 2.1 regulate blockage by external ba.

Lee YM et al.

The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2009

Ser165 in the second transmembrane region of the Kir2.1 channel determines its susceptibility to blockade by intracellular Mg2+.

Fujiwara Y et al.

The Journal of General Physiology, 2002

Residues beyond the selectivity filter of the K+ channel kir2.1 regulate permeation and block by external Rb+ and Cs+.

Thompson GA et al.

The Journal of Physiology, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."