Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.K182Q
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KCNJ2

NM_000891.3:p.K182Q

Associated Papers

From Crosstalk to Synergism: The Combined Effect of Cholesterol and PI(4,5)P2 on Inwardly Rectifying Potassium Channels.

Bukiya AN et al.

Advances in Experimental Medicine and Biology, 2023

Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference.

Koepple C et al.

The Journal of Pharmacology and Experimental Therapeutics, 2017

Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.

Xynogalos P et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2014

Phosphoinositide regulation of inward rectifier potassium (Kir) channels.

Fürst O et al.

Frontiers in Physiology, 2014

Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.

López-Izquierdo A et al.

Pflugers Archiv : European Journal of Physiology, 2011

Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol.

Epshtein Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."