Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ2
Variant:p.E224Q
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KCNJ2

NM_000891.3:p.E224Q

Associated Papers

Gating of the kir2.1 channel at the bundle crossing region by intracellular spermine and other cations.

Huang CW et al.

Journal of Cellular Physiology, 2014

The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.

Huang CW et al.

Pflugers Archiv : European Journal of Physiology, 2014

Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels.

Chang HK et al.

The Journal of Membrane Biology, 2007

Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.

Fujiwara Y et al.

The Journal of General Physiology, 2006

A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation.

Chang HK et al.

Biophysical Journal, 2005

Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel.

Xie LH et al.

The Journal of Physiology, 2004

C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1.

Taglialatela M et al.

The Embo Journal, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."