Associated Papers
Gating and modulation of an inward-rectifier potassium channel.
Jogini V et al.
The Journal of General Physiology, 2023
A small viral potassium ion channel with an inherent inward rectification.
Eckert D et al.
Channels (austin, Tex.), 2019
The molecular basis of chloroethylclonidine block of inward rectifier (Kir2.1 and Kir4.1) K(+) channels.
Rodríguez-Menchaca AA et al.
Pharmacological Reports : Pr, 2016
Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.
Huang CW et al.
Pflugers Archiv : European Journal of Physiology, 2015
Driving force-dependent block by internal Ba(2+) on the Kir2.1 channel: Mechanistic insight into inward rectification.
Hsieh CP et al.
Biophysical Chemistry, 2015
Gating of the kir2.1 channel at the bundle crossing region by intracellular spermine and other cations.
Huang CW et al.
Journal of Cellular Physiology, 2014
The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.
Huang CW et al.
Pflugers Archiv : European Journal of Physiology, 2014
Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.
López-Izquierdo A et al.
Pflugers Archiv : European Journal of Physiology, 2011
Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
Ponce-Balbuena D et al.
The Journal of Pharmacology and Experimental Therapeutics, 2009
Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.
Ishihara K et al.
The Journal of Physiology, 2007
Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels.
Chang HK et al.
The Journal of Membrane Biology, 2007
Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.
Fujiwara Y et al.
The Journal of General Physiology, 2006
Electrostatics in the cytoplasmic pore produce intrinsic inward rectification in kir2.1 channels.
Yeh SH et al.
The Journal of General Physiology, 2005
A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation.
Chang HK et al.
Biophysical Journal, 2005
Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel.
Xie LH et al.
The Journal of Physiology, 2004
Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel.
Dibb KM et al.
The Journal of Biological Chemistry, 2003
Conformational changes in Kir2.1 channels during NH4+-induced inactivation.
Chang HK et al.
The Journal of Biological Chemistry, 2003
Ser165 in the second transmembrane region of the Kir2.1 channel determines its susceptibility to blockade by intracellular Mg2+.
Fujiwara Y et al.
The Journal of General Physiology, 2002
Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel.
Kubo Y et al.
The Journal of Physiology, 2001
Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1.
Lee JK et al.
The Journal of General Physiology, 1999
Inwardly rectifying potassium channels expressed by gene transfection into the green Monkey kidney cell line COS-1.
Omori K et al.
The Journal of Physiology, 1997
A weakly inward rectifying potassium channel of the salmon brain. Glutamate 179 in the second transmembrane domain is insufficient for strong rectification.
Kubo Y et al.
The Journal of Biological Chemistry, 1996
Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation.
Reuveny E et al.
Biophysical Journal, 1996
Determination of the subunit stoichiometry of an inwardly rectifying potassium channel.
Yang J et al.
Neuron, 1995
C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1.
Taglialatela M et al.
The Embo Journal, 1995