Associated Papers
Coupling sensor to enzyme in the voltage sensing phosphatase.
Yu Y et al.
Nature Communications, 2024
Ion channel regulation by phosphoinositides analyzed with VSPs-PI(4,5)P2 affinity, phosphoinositide selectivity, and PI(4,5)P2 pool accessibility.
Rjasanow A et al.
Frontiers in Pharmacology, 2015
The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.
Huang CW et al.
Pflugers Archiv : European Journal of Physiology, 2014
Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore.
Amorós I et al.
Biochemical Pharmacology, 2013
A glutamate switch controls voltage-sensitive phosphatase function.
Liu L et al.
Nature Structural & Molecular Biology, 2012
Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP.
Kohout SC et al.
Nature Chemical Biology, 2010
Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol.
Epshtein Y et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009
Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels.
Chang HK et al.
The Journal of Membrane Biology, 2007
Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.
Fujiwara Y et al.
The Journal of General Physiology, 2006
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor.
Murata Y et al.
Nature, 2005
In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).
Hardie RC et al.
The Journal of Biological Chemistry, 2004
Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions.
Zhang H et al.
Nature Cell Biology, 1999
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