Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ4
Variant:p.E291A
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KCNJ4

NM_152868.3:p.E291A

Associated Papers

Verapamil inhibits Kir2.3 channels by binding to the pore and interfering with PIP2 binding.

Xynogalos P et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2023

Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference.

Koepple C et al.

The Journal of Pharmacology and Experimental Therapeutics, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."