Associated Papers
Determinants of trafficking, conduction, and disease within a K+ channel revealed through multiparametric deep mutational scanning.
Coyote-Maestas W et al.
Elife, 2022
35639599 (PubMed )
Supplement: elife-76903-data1.zip › SourceData › input_data › KCNJ_Gnomad_0325322.xlsx › Sheet1
Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore.
Amorós I et al.
Biochemical Pharmacology, 2013
Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol.
Epshtein Y et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009
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