Varaico: Literature-Extracted Genetic Variants

Gene:KCNJ5
Variant:p.L77I
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KCNJ5

NM_000890.5:p.L77I

Associated Papers

Structural determinants of the direct inhibition of GIRK channels by Sigma-1 receptor antagonist.

Liu C et al.

The Journal of Biological Chemistry, 2024

A novel small-molecule selective activator of homomeric GIRK4 channels.

Cui M et al.

The Journal of Biological Chemistry, 2022

Ivermectin activates GIRK channels in a PIP2 -dependent, Gβγ -independent manner and an amino acid residue at the slide helix governs the activation.

Chen IS et al.

The Journal of Physiology, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."