Associated Papers
An In Silico Investigation of the Pathogenic G151R G Protein-Gated Inwardly Rectifying K+ Channel 4 Variant to Identify Small Molecule Modulators.
Pitsillou E et al.
Biology, 2024
Identification of Potential Modulators of a Pathogenic G Protein-Gated Inwardly Rectifying K+ Channel 4 Mutant: In Silico Investigation in the Context of Drug Discovery for Hypertension.
Pitsillou E et al.
Molecules (basel, Switzerland), 2023
The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents.
Xu Y et al.
The Journal of Biological Chemistry, 2020
The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel Trafficking.
Choveau FS et al.
Plos One, 2015
Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.
Vivaudou M et al.
The Journal of Biological Chemistry, 1997
Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit.
Chan KW et al.
Proceedings of the National Academy of Sciences of the United States of America, 1996
A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels.
Cui M et al.
The Journal of Biological Chemistry, 0
33713702 (PubMed )
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