Associated Papers
Somatic drivers in aldosterone-producing adenomas and nodules: Insights from a Brazilian cohort of primary aldosteronism.
Guimaraes AG et al.
The Journal of Clinical Endocrinology and Metabolism, 2026
Primary Aldosteronism: Small Molecule Antagonists of Mutant KCNJ5 Potassium Channels.
Mir-Bashiri S et al.
Hypertension (dallas, Tex. : 1979), 2025
Molecular investigation of primary aldosteronism: exploring genetic heterogeneity in understudied populations.
Maeda LK et al.
Archives of Endocrinology and Metabolism, 2025
Ion channel mutations and cancer.
Cao X et al.
Biochemistry and Biophysics Reports, 2025
ccfDNA analysis for the classification of adrenocortical adenomas.
Xu M et al.
Journal of Endocrinological Investigation, 2025
Prevalence of KCNJ5 mutations in aldosterone-producing adenomas among Malaysian primary aldosteronism patients: Genotype-phenotype correlation.
Mohd Rizam NS et al.
The Malaysian Journal of Pathology, 2025
Multiomics analysis unveils the cellular ecosystem with clinical relevance in aldosterone-producing adenomas with KCNJ5 mutations.
Yokomoto-Umakoshi M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism.
Mai X et al.
Endocrine Journal, 2025
Evolutionary Characteristics in Primary Aldosteronism Patients.
Gao Y et al.
Hypertension (dallas, Tex. : 1979), 2025
The adrenal gland and primary aldosteronism: anatomy, steroidogenesis, regulation, and genetic insights.
Long KC et al.
Frontiers in Endocrinology, 2025
Aldosterone-producing Multiple Micronodules With Several Different KCNJ5 Pathogenic Variants.
Oiwa Y et al.
Jcem Case Reports, 2024
An In Silico Investigation of the Pathogenic G151R G Protein-Gated Inwardly Rectifying K+ Channel 4 Variant to Identify Small Molecule Modulators.
Pitsillou E et al.
Biology, 2024
Molecular and Genetics Perspectives on Primary Adrenocortical Hyperfunction Disorders.
Kim S et al.
International Journal of Molecular Sciences, 2024
Severe hydronephrosis complicated with primary aldosteronism: a case report and review of the literature.
Sun J et al.
Journal of Medical Case Reports, 2024
Double CYP11B1/CYP11B2 Immunohistochemistry and Detection of KCNJ5 Mutations in Primary Aldosteronism.
Caroccia B et al.
The Journal of Clinical Endocrinology and Metabolism, 2024
Adrenocortical Tumor Associated With Pathogenic Variant in KCNJ5 and DNA Methylation of CYP11B2 in Primary Aldosteronism.
Aiga K et al.
Jcem Case Reports, 2024
KCNJ5 mutations in familial and non-familial primary aldosteronism.
Al-Salameh A
European Journal of Endocrinology, 2024
Familial hyperaldosteronism: an European Reference Network on Rare Endocrine Conditions clinical practice guideline.
Mulatero P et al.
European Journal of Endocrinology, 2024
Differences in the clinical and hormonal presentation of patients with familial and sporadic primary aldosteronism.
Araujo-Castro M et al.
Frontiers in Endocrinology, 2024
Direct modulation of G protein-gated inwardly rectifying potassium (GIRK) channels.
Nguyen H et al.
Frontiers in Physiology, 2024
Identification of Potential Modulators of a Pathogenic G Protein-Gated Inwardly Rectifying K+ Channel 4 Mutant: In Silico Investigation in the Context of Drug Discovery for Hypertension.
Pitsillou E et al.
Molecules (basel, Switzerland), 2023
Primary aldosteronism: molecular medicine meets public health.
Azizan EAB et al.
Nature Reviews. Nephrology, 2023
Nutrigenomics of inward rectifier potassium channels.
Ferreira G et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2023
Relevance of KCNJ5 in Pathologies of Heart Disease.
Meyer KM et al.
International Journal of Molecular Sciences, 2023
Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
Wu X et al.
Nature Genetics, 2023
[The genetic background of primary aldosteronism].
Vékony B et al.
Orvosi Hetilap, 2023
A genomic deep field view of hypertension.
Garimella PS et al.
Kidney International, 2023
Recurrence of Primary Aldosteronism After Surgery in Aldosterone-producing Adenoma With KCNJ5 Gene Mutation.
Aiga K et al.
Jcem Case Reports, 2023
Cardiovascular and metabolic characters of KCNJ5 somatic mutations in primary aldosteronism.
Chang YY et al.
Frontiers in Endocrinology, 2023
Genetic Dissection of Primary Aldosteronism in a Patient With MEN1 and Ipsilateral Adrenocortical Carcinoma and Adenoma.
Parisien-La Salle S et al.
The Journal of Clinical Endocrinology and Metabolism, 2022
Exome sequencing unravels genetic variants associated with chronic kidney disease in Saudi Arabian patients.
Al-Hamed MH et al.
Human Mutation, 2022
Identification of risk loci for primary aldosteronism in genome-wide association studies.
Le Floch E et al.
Nature Communications, 2022
Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.
Pitsava G et al.
Current Cardiology Reports, 2022
Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.
Nanba K et al.
The Journal of Clinical Endocrinology and Metabolism, 2022
Pathophysiology of bilateral hyperaldosteronism.
Nanba K et al.
Current Opinion in Endocrinology, Diabetes, and Obesity, 2022
A novel small-molecule selective activator of homomeric GIRK4 channels.
Cui M et al.
The Journal of Biological Chemistry, 2022
Determinants of trafficking, conduction, and disease within a K+ channel revealed through multiparametric deep mutational scanning.
Coyote-Maestas W et al.
Elife, 2022
Hypomethylation associated vitamin D receptor expression in ATP1A1 mutant aldosterone-producing adenoma.
Nanao Y et al.
Molecular and Cellular Endocrinology, 2022
Genetics of Primary Aldosteronism.
Scholl UI
Hypertension (dallas, Tex. : 1979), 2022
A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5).
Shalomov B et al.
The Journal of Physiology, 2022
How do Kir3.4 mutations cause hereditary hyperaldosteronism?
Kubo Y
The Journal of Physiology, 2022
A novel ion conducting route besides the central pore in an inherited mutant of G-protein-gated inwardly rectifying K+ channel.
Chen IS et al.
The Journal of Physiology, 2022
False-negative aldosterone-to-renin ratio in a primary aldosteronism patient complicated with primary polydipsia: case report.
Zheng C et al.
Gland Surgery, 2022
A Novel Somatic Mutation of CACNA1H p.V1937M in Unilateral Primary Hyperaldosteronism.
Tseng CS et al.
Frontiers in Endocrinology, 2022
Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome.
Santana LS et al.
Frontiers in Endocrinology, 2022