Associated Papers
Use of a Molecular Switch Probe to Activate or Inhibit GIRK1 Heteromers In Silico Reveals a Novel Gating Mechanism.
Gazgalis D et al.
International Journal of Molecular Sciences, 2022
A selectivity filter mutation provides insights into gating regulation of a K+ channel.
Friesacher T et al.
Communications Biology, 2022
35411015 (PubMed )
Supplement: 42003_2022_3303_MOESM1_ESM.pdf
On the mechanism of GIRK2 channel gating by phosphatidylinositol bisphosphate, sodium, and the Gβγ dimer.
Li D et al.
The Journal of Biological Chemistry, 2019
Non-sedating antihistamines block G-protein-gated inwardly rectifying K+ channels.
Chen IS et al.
British Journal of Pharmacology, 2019
The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel.
Meng XY et al.
Scientific Reports, 2016
The selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel.
Claydon TW et al.
The Journal of Biological Chemistry, 2003
The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment.
Jin T et al.
Molecular Cell, 2002
Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels.
Sadja R et al.
Neuron, 2001
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