Associated Papers
From Crosstalk to Synergism: The Combined Effect of Cholesterol and PI(4,5)P2 on Inwardly Rectifying Potassium Channels.
Bukiya AN et al.
Advances in Experimental Medicine and Biology, 2023
On the mechanism of GIRK2 channel gating by phosphatidylinositol bisphosphate, sodium, and the Gβγ dimer.
Li D et al.
The Journal of Biological Chemistry, 2019
Synergistic activation of G protein-gated inwardly rectifying potassium channels by cholesterol and PI(4,5)P2.
Bukiya AN et al.
Biochimica Et Biophysica Acta. Biomembranes, 2017
The ICl,swell inhibitor DCPIB blocks Kir channels that possess weak affinity for PIP2.
Deng W et al.
Pflugers Archiv : European Journal of Physiology, 2016
Cholesterol increases the open probability of cardiac KACh currents.
Bukiya AN et al.
Biochimica Et Biophysica Acta, 2015
A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2).
Rosenhouse-Dantsker A et al.
Nature Chemical Biology, 2008
PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.
Lopes CM et al.
The Journal of Physiology, 2005
Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction.
Zhang L et al.
The Journal of Biological Chemistry, 2004
The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment.
Jin T et al.
Molecular Cell, 2002
Identification of critical residues controlling G protein-gated inwardly rectifying K(+) channel activity through interactions with the beta gamma subunits of G proteins.
He C et al.
The Journal of Biological Chemistry, 2002
Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions.
Zhang H et al.
Nature Cell Biology, 1999
Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop.
Rosenhouse-Dantsker A et al.
Channels (austin, Tex.), 0
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