Varaico: Literature-Extracted Genetic Variants

Gene:KCNK1
Variant:p.T118I
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KCNK1

NM_002245.4:p.T118I

Associated Papers

The Effect of TWIK-1 Two Pore Potassium Channels on Cardiomyocytes in Low Extracellular Potassium Conditions.

Liu P et al.

Frontiers in Bioscience (landmark Edition), 2023

Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel.

Nematian-Ardestani E et al.

The Journal of Biological Chemistry, 2020

Structural properties determining low K+ affinity of the selectivity filter in the TWIK1 K+ channel.

Tsukamoto H et al.

The Journal of Biological Chemistry, 2018

Altered and dynamic ion selectivity of K+ channels in cell development and excitability.

Chen H et al.

Trends in Pharmacological Sciences, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."