Varaico: Literature-Extracted Genetic Variants

Gene:KCNK13
Variant:p.Y273F
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KCNK13

NM_022054.4:p.Y273F

Associated Papers

Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics.

Rödström KEJ et al.

Nature Structural & Molecular Biology, 2025

Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site.

Roy-Chowdhury S et al.

Nature Structural & Molecular Biology, 2025

The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel.

Riel EB et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Structure of the human K2P13.1(THIK-1) channel reveals a novel hydrophilic pore restriction and lipid cofactor site.

Roy-Chowdhury S et al.

Biorxiv : the Preprint Server for Biology, 2024

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