Associated Papers
The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Nakhe AY et al.
Elife, 2024
The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Nakhe AY et al.
Biorxiv : the Preprint Server for Biology, 2024
Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.
Huang YC et al.
Journal of Personalized Medicine, 2023
37763159 (PubMed )
Supplement: jpm-13-01392-s001.zip › Supplementary_Table_S3.xlsx › Variants
Alkaline-sensitive two-pore domain potassium channels form functional heteromers in pancreatic β-cells.
Khoubza L et al.
The Journal of Biological Chemistry, 2022
Beta-Cell Ion Channels and Their Role in Regulating Insulin Secretion.
Thompson B et al.
Comprehensive Physiology, 2021
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
Suzuki K et al.
Nature Genetics, 2019
Progress in defining the genetic contribution to type 2 diabetes susceptibility.
Morris AP
Current Opinion in Genetics & Development, 2018
TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion.
Vierra NC et al.
Molecular Metabolism, 2018
Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.
O'Beirne SL et al.
Plos One, 2018
30212457 (PubMed )
Supplement: pone.0199837.s005.pdf
TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis.
Vierra NC et al.
Science Signaling, 2017
Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.
Dickerson MT et al.
Plos One, 2017
Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis.
Vierra NC et al.
Diabetes, 2015
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