Associated Papers
Potassium Channels as Therapeutic Targets in Pulmonary Arterial Hypertension.
Redel-Traub G et al.
Biomolecules, 2022
Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension.
Le Ribeuz H et al.
Biomolecules, 2020
TASK channels: channelopathies, trafficking, and receptor-mediated inhibition.
Inoue M et al.
Pflugers Archiv : European Journal of Physiology, 2020
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Rödström KEJ et al.
Nature, 2020
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
Characterization and regulation of wild-type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertension.
Cunningham KP et al.
The Journal of Physiology, 2019
Exome data clouds the pathogenicity of genetic variants in Pulmonary Arterial Hypertension.
Abbasi Y et al.
Molecular Genetics & Genomic Medicine, 2018
Pulmonary artery hypertension in childhood: The transforming growth factor-β superfamily-related genes.
Yuan SM
Pediatrics and Neonatology, 2018
TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.
Olschewski A et al.
The European Respiratory Journal, 2017
TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis.
Vierra NC et al.
Science Signaling, 2017
The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery.
Bohnen MS et al.
Journal of the American Heart Association, 2017
A systematic review of genetic mutations in pulmonary arterial hypertension.
Garcia-Rivas G et al.
Bmc Medical Genetics, 2017
A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension.
Higasa K et al.
Bmc Pulmonary Medicine, 2017
An homozygous mutation in KCNK3 is associated with an aggressive form of hereditary pulmonary arterial hypertension.
Navas Tejedor P et al.
Clinical Genetics, 2017
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
Molnár J et al.
Plos One, 2016
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.
Machado RD et al.
Human Mutation, 2015
The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.
Decher N et al.
Pflugers Archiv : European Journal of Physiology, 2015
Genetics of pulmonary hypertension.
Best DH et al.
Current Opinion in Cardiology, 2014
KCNK3: new gene target for pulmonary hypertension?
Girerd B et al.
Expert Review of Respiratory Medicine, 2014
The genetic basis of pulmonary arterial hypertension.
Ma L et al.
Human Genetics, 2014
Genetics: Potassium channelopathy implicated in the pathogenesis of familial PAH.
Roberts A
Nature Reviews. Cardiology, 2013
A novel channelopathy in pulmonary arterial hypertension.
Ma L et al.
The New England Journal of Medicine, 2013