Associated Papers
Potassium Channels as Therapeutic Targets in Pulmonary Arterial Hypertension.
Redel-Traub G et al.
Biomolecules, 2022
Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension.
Le Ribeuz H et al.
Biomolecules, 2020
TASK channels: channelopathies, trafficking, and receptor-mediated inhibition.
Inoue M et al.
Pflugers Archiv : European Journal of Physiology, 2020
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Rödström KEJ et al.
Nature, 2020
Exome data clouds the pathogenicity of genetic variants in Pulmonary Arterial Hypertension.
Abbasi Y et al.
Molecular Genetics & Genomic Medicine, 2018
TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.
Olschewski A et al.
The European Respiratory Journal, 2017
The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery.
Bohnen MS et al.
Journal of the American Heart Association, 2017
A systematic review of genetic mutations in pulmonary arterial hypertension.
Garcia-Rivas G et al.
Bmc Medical Genetics, 2017
28768485 (PubMed )
Supplement: 12881_2017_440_MOESM1_ESM.xlsx › table-mutations-per-gene
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
Molnár J et al.
Plos One, 2016
26986070 (PubMed )
Supplement: pone.0151760.s001.xlsx › disease
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.
Machado RD et al.
Human Mutation, 2015
Breathing Stimulant Compounds Inhibit TASK-3 Potassium Channel Function Likely by Binding at a Common Site in the Channel Pore.
Chokshi RH et al.
Molecular Pharmacology, 2015
Genetics of pulmonary hypertension.
Best DH et al.
Current Opinion in Cardiology, 2014
Genetics: Potassium channelopathy implicated in the pathogenesis of familial PAH.
Roberts A
Nature Reviews. Cardiology, 2013
A novel channelopathy in pulmonary arterial hypertension.
Ma L et al.
The New England Journal of Medicine, 2013
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