Associated Papers
Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk.
Harvey ML et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
41445606 (PubMed )
Supplement: media-2.xlsx › File_S1
Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.
Walsh R et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2021
32893267 (PubMed )
Supplement: 41436_2020_946_MOESM2_ESM.xlsx › S4
Molecular determinants of Kv7.1/KCNE1 channel inhibition by amitriptyline.
Villatoro-Gómez K et al.
Biochemical Pharmacology, 2018
KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.
Wrobel E et al.
Nature Communications, 2016
Molecular determinants of KCNQ1 channel block by a benzodiazepine.
Seebohm G et al.
Molecular Pharmacology, 2003
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