Associated Papers
Ion permeation through a narrow cavity constriction in KCNQ1 channels: Mechanism and implications for pathogenic variants.
Mkrtchyan L et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Identification of mutations in canine oral mucosal melanomas by exome sequencing and comparison with human melanomas.
Dagli MLZ et al.
Scientific Reports, 2024
Targeting the IKs Channel PKA Phosphorylation Axis to Restore Its Function in High-Risk LQT1 Variants.
Zhong L et al.
Circulation Research, 2024
Two-stage electro-mechanical coupling of a KV channel in voltage-dependent activation.
Hou P et al.
Nature Communications, 2020
Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome.
Brewer KR et al.
Frontiers in Pharmacology, 2020
Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.
Cui J
Biophysical Journal, 2016
Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.
Ma LJ et al.
Biophysical Journal, 2011
Differential roles of S6 domain hinges in the gating of KCNQ potassium channels.
Seebohm G et al.
Biophysical Journal, 2006
Molecular determinants of KCNQ1 channel block by a benzodiazepine.
Seebohm G et al.
Molecular Pharmacology, 2003
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