Associated Papers
Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk.
Harvey ML et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
41445606 (PubMed )
Supplement: media-2.xlsx › File_S2
Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.
Cui J
Biophysical Journal, 2016
An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1.
Yang T et al.
Molecular Pharmacology, 2013
Opposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels.
Choveau FS et al.
Frontiers in Pharmacology, 2012
Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.
Ma LJ et al.
Biophysical Journal, 2011
KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain.
Choveau FS et al.
The Journal of Biological Chemistry, 2011
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure.
Labro AJ et al.
The Journal of Biological Chemistry, 2011
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