Associated Papers
Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk.
Harvey ML et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
41445606 (PubMed )
Supplement: media-2.xlsx › File_S2
Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.
Ma D et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
Willegems K et al.
Nature Communications, 2022
Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.
Ma LJ et al.
Biophysical Journal, 2011
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure.
Labro AJ et al.
The Journal of Biological Chemistry, 2011
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