Associated Papers
KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
Kiper AK et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels.
Lange W et al.
Molecular Pharmacology, 2009
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.
Lerche C et al.
Molecular Pharmacology, 2007
Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels.
Seebohm G et al.
The Journal of Physiology, 2005
Molecular determinants of KCNQ1 channel block by a benzodiazepine.
Seebohm G et al.
Molecular Pharmacology, 2003
Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome.
Seebohm G et al.
The Journal of Biological Chemistry, 2001
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