Varaico: Literature-Extracted Genetic Variants

Gene:KCNQ1
Variant:p.V310A
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KCNQ1

NM_000218.3:p.V310A

Associated Papers

Mechanism of external K+ sensitivity of KCNQ1 channels.

Abrahamyan A et al.

The Journal of General Physiology, 2023

Molecular determinants of Kv7.1/KCNE1 channel inhibition by amitriptyline.

Villatoro-Gómez K et al.

Biochemical Pharmacology, 2018

Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.

Ma LJ et al.

Biophysical Journal, 2011

Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels.

Seebohm G et al.

The Journal of Physiology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."