Varaico: Literature-Extracted Genetic Variants

Gene:KCNQ1
Variant:p.V324A
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KCNQ1

NM_000218.3:p.V324A

Associated Papers

Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk.

Harvey ML et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

41445606 (PubMed )
Supplement: media-2.xlsx › File_S2

A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes.

Chan M et al.

Elife, 2023

An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1.

Yang T et al.

Molecular Pharmacology, 2013

Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.

Ma LJ et al.

Biophysical Journal, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."