Associated Papers
KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
Kiper AK et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements.
Chen L et al.
Frontiers in Physiology, 2022
The membrane protein KCNQ1 potassium ion channel: Functional diversity and current structural insights.
Dixit G et al.
Biochimica Et Biophysica Acta. Biomembranes, 2020
KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.
Wrobel E et al.
Nature Communications, 2016
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.
Lerche C et al.
Molecular Pharmacology, 2007
Susceptibility genes and modifiers for cardiac arrhythmias.
Kääb S et al.
Cardiovascular Research, 2005
KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction.
Jeron A et al.
Journal of Molecular and Cellular Cardiology, 2004
Molecular determinants of KCNQ1 channel block by a benzodiazepine.
Seebohm G et al.
Molecular Pharmacology, 2003
Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols.
Lerche C et al.
British Journal of Pharmacology, 2000
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