Associated Papers
To Modify or Not to Modify: Allele-Specific Effects of 3'UTR-KCNQ1 Single Nucleotide Polymorphisms on Clinical Phenotype in a Long QT 1 Founder Population Segregating a Dominant-Negative Mutation.
Winbo A et al.
Journal of the American Heart Association, 2022
Deciphering Common Long QT Syndrome Using CRISPR/Cas9 in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Song Y et al.
Frontiers in Cardiovascular Medicine, 2022
The Role of KCNQ1 Mutations and Maternal Beta Blocker Use During Pregnancy in the Growth of Children With Long QT Syndrome.
Huttunen H et al.
Frontiers in Endocrinology, 2018
Massively Parallel Sequencing of Genes Implicated in Heritable Cardiac Disorders: A Strategy for a Small Diagnostic Laboratory.
Leong IUS et al.
Medical Sciences (basel, Switzerland), 2017
Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes.
Kuusela J et al.
Biology Open, 2017
Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3' Untranslated Region of KCNQ1?
Crotti L et al.
Circulation. Cardiovascular Genetics, 2016
Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population.
Lahtinen AM et al.
Annals of Medicine, 2013
A presumably benign human ether-a-go-go-related gene mutation (R176W) with a malignant primary manifestation of long QT syndrome.
Donner BC et al.
Cardiology in the Young, 2012
Cloninger's temperament traits and inherited long QT syndrome.
Määttänen I et al.
Journal of Psychosomatic Research, 2011
KCNE1 D85N polymorphism--a sex-specific modifier in type 1 long QT syndrome?
Lahtinen AM et al.
Bmc Medical Genetics, 2011
Recurrent and Founder Mutations in the Netherlands: the Long-QT Syndrome.
Hofman N et al.
Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2011
High prevalence of four long QT syndrome founder mutations in the Finnish population.
Marjamaa A et al.
Annals of Medicine, 2009
Long QT and Brugada syndrome gene mutations in New Zealand.
Chung SK et al.
Heart Rhythm, 2007
Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.
Paavonen KJ et al.
International Journal of Cardiology, 2007
Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.
Lehtonen A et al.
Heart Rhythm, 2007
Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients.
Fodstad H et al.
Annals of Medicine, 2006
Four potassium channel mutations account for 73% of the genetic spectrum underlying long-QT syndrome (LQTS) and provide evidence for a strong founder effect in Finland.
Fodstad H et al.
Annals of Medicine, 2004