Varaico: Literature-Extracted Genetic Variants

Gene:KDM6A
Variant:p.D336G
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KDM6A

NM_001291415.2:p.D336G

Associated Papers

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules.

Liu X et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2025

A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Chen S et al.

Genome Research, 2022

34963661 (PubMed )
Supplement: supp_gr.275437.121_Supplementary_Table_1.xlsx › Non-recurrent_variants

Lysine Demethylase KDM6A in Differentiation, Development, and Cancer.

Tran N et al.

Molecular and Cellular Biology, 2020

Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.

Kato H et al.

Oncogene, 2020

Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing.

Wu S et al.

Oncotarget, 2016

26625313 (PubMed )
Supplement: oncotarget-07-2629-s002.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."