Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.R470S
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KEAP1

NM_203500.2:p.R470S

Associated Papers

Genomic profiling in hepatocellular carcinoma: a real-world retrospective analysis.

Salani F et al.

Esmo Open, 2025

41167083 (PubMed )
Supplement: mmc4.xlsx › Table_S10B

The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs).

Zhang L et al.

Elife, 2024

39688960 (PubMed )
Supplement: elife-99340-supp1.xlsx › CDN.Missense.gnomad

Clinical perspectives on the value of testing for STK11 and KEAP1 mutations in advanced NSCLC.

Shiller M et al.

Frontiers in Oncology, 2024

39703851 (PubMed )
Supplement: DataSheet2.xlsx › Supplemental_data

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Supp._Table_5

The Mutational Landscape of Cancer's Vulnerability to Ionizing Radiation.

Gopal P et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2022

KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability.

Wilson CJ et al.

International Journal of Molecular Sciences, 2021

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Torrente L et al.

Redox Biology, 2020

32007910 (PubMed )
Supplement: mmc3.xlsx › Table_2_LuAD

MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.

Cai W et al.

Bmc Genomics, 2018

30075702 (PubMed )
Supplement: 12864_2018_4958_MOESM4_ESM.xlsx › Supplementary_Table_4

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells.

Testa U et al.

Cancers, 2018

30060526 (PubMed )
Supplement: cancers-10-00248-s001.docx

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Berger AH et al.

Cancer Cell, 2016

Functionally Assessing Candidate Drivers Advances Precision Cancer Medicine.

Scott KL et al.

Cancer Cell, 2016

Cross-cancer profiling of molecular alterations within the human autophagy interaction network.

Lebovitz CB et al.

Autophagy, 2015

26208877 (PubMed )
Supplement: kaup-11-09-1067362-s001.zip › 1067362_supplemental_files › 2014AUTO0485R1-s03.xlsx › LUAD-mutations
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."