Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.R362Q
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KEAP1

NM_203500.2:p.R362Q

Associated Papers

Integrated histopathologic modeling of detailed tumor subtypes and actionable biomarkers.

Boehm KM et al.

Biorxiv : the Preprint Server for Biology, 2025

KEAP1 mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancer.

Bambach NE et al.

Frontiers in Oncology, 2025

41573641 (PubMed )
Supplement: Table2.xlsx › Sheet1

Exploring Genomic Biomarkers for Pembrolizumab Response: A Real-World Approach and Patient Similarity Network Analysis Reveal DNA Response and Repair Gene Mutations as a Signature.

Filetti M et al.

Cancers, 2024

39682144 (PubMed )
Supplement: cancers-16-03955-s001.zip › Table_S4.xlsx › Table_S4

Clear Cell Adenocarcinoma of Urethra: Clinical and Pathologic Implications and Characterization of Molecular Aberrations.

Song B et al.

Cancer Research and Treatment, 2024

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma Development.

Wang Q et al.

Journal of Cancer, 2024

38370388 (PubMed )
Supplement: jcav15p1687s1.zip › Supplementary_Materials › Clinical_and_Genomic_Data.xlsx › Gene_mutation

Clinical perspectives on the value of testing for STK11 and KEAP1 mutations in advanced NSCLC.

Shiller M et al.

Frontiers in Oncology, 2024

39703851 (PubMed )
Supplement: DataSheet2.xlsx › Supplemental_data

EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.

Jin R et al.

Frontiers in Oncology, 2021

34195081 (PubMed )
Supplement: Table_2.xlsx › EGFR-Mutant_ADC

Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer.

Abdel-Wahab R et al.

Scientific Reports, 2020

33328484 (PubMed )
Supplement: 41598_2020_77939_MOESM1_ESM.xlsx › Sheet1

Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer.

Scholl SM et al.

Ebiomedicine, 2020

33096476 (PubMed )
Supplement: mmc2.xlsx › RAIDS_algo_filtering_wLOH_forma

Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non-Small Cell Lung Cancer.

Jia Q et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

32382482 (PubMed )
Supplement: ADVS-7-1903410-s004.xlsx › Sup2_Somatic_reportDetail

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Torrente L et al.

Redox Biology, 2020

32007910 (PubMed )
Supplement: mmc2.xlsx › Table_1_LuSCC

Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Koyama T et al.

Bmc Cancer, 2019

30709382 (PubMed )
Supplement: 12885_2019_5313_MOESM2_ESM.xlsx › supplementary_2_filtered

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden.

Chalmers ZR et al.

Genome Medicine, 2017

28420421 (PubMed )
Supplement: 13073_2017_424_MOESM7_ESM.xlsx › Sheet1

Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.

Khan H et al.

The Biochemical Journal, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."