Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.K312R
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KEAP1

NM_203500.2:p.K312R

Associated Papers

SUMOylation of the ubiquitin ligase component KEAP1 at K39 upregulates NRF2 and its target function in lung cancer cell proliferation.

Yang H et al.

The Journal of Biological Chemistry, 2023

P301S-hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau-induced synaptic toxicities.

Xie JZ et al.

Clinical and Translational Medicine, 2022

35917404 (PubMed )
Supplement: CTM2-12-e1003-s001.docx
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."