Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.H311R
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KEAP1

NM_203500.2:p.H311R

Associated Papers

Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer.

Pillai R et al.

Science Advances, 2024

38536921 (PubMed )
Supplement: sciadv.adm9859_sm.pdf

Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer.

Pillai R et al.

Biorxiv : the Preprint Server for Biology, 2023

EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion.

Marzio A et al.

Cell, 2022

KEAP1/NFE2L2 Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition.

Binkley MS et al.

Cancer Discovery, 2020

Phase and context shape the function of composite oncogenic mutations.

Gorelick AN et al.

Nature, 2020

32461694 (PubMed )
Supplement: NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx › Table_S2._Composite_mutations
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."