Associated Papers
KEAP1 mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancer.
Bambach NE et al.
Frontiers in Oncology, 2025
41573641 (PubMed )
Supplement: Table2.xlsx › Sheet1
Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
Ziros PG et al.
Thyroid : Official Journal of the American Thyroid Association, 2021
Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer.
Renaud CO et al.
Frontiers in Endocrinology, 2019
Identification of a KEAP1 germline mutation in a family with multinodular goitre.
Teshiba R et al.
Plos One, 2013
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