Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.Q284L
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KEAP1

NM_203500.2:p.Q284L

Associated Papers

PPIA dictates NRF2 stability to promote lung cancer progression.

Lu W et al.

Nature Communications, 2024

38830868 (PubMed )
Supplement: 41467_2024_48364_MOESM1_ESM.docx

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

Somatic Evolution in Non-neoplastic IBD-Affected Colon.

Olafsson S et al.

Cell, 2020

32697969 (PubMed )
Supplement: mmc4.xlsx › A__TCGA_hotspots

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Torrente L et al.

Redox Biology, 2020

32007910 (PubMed )
Supplement: mmc3.xlsx › Table_2_LuAD

WDR23 regulates NRF2 independently of KEAP1.

Lo JY et al.

Plos Genetics, 2017

28453520 (PubMed )
Supplement: pgen.1006762.s011.pdf

Cross-cancer profiling of molecular alterations within the human autophagy interaction network.

Lebovitz CB et al.

Autophagy, 2015

26208877 (PubMed )
Supplement: kaup-11-09-1067362-s001.zip › 1067362_supplemental_files › 2014AUTO0485R1-s03.xlsx › LUAD-mutations

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.

Taguchi K et al.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."