Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.R234W
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KEAP1

NM_203500.2:p.R234W

Associated Papers

Integrated histopathologic modeling of detailed tumor subtypes and actionable biomarkers.

Boehm KM et al.

Biorxiv : the Preprint Server for Biology, 2025

Clinical perspectives on the value of testing for STK11 and KEAP1 mutations in advanced NSCLC.

Shiller M et al.

Frontiers in Oncology, 2024

39703851 (PubMed )
Supplement: DataSheet2.xlsx › Supplemental_data

Blood tumor mutational burden and dynamic changes in circulating tumor DNA predict response to pembrolizumab treatment in advanced non-small cell lung cancer.

Stensgaard S et al.

Translational Lung Cancer Research, 2023

Genomic features of renal cell carcinoma developed during end-stage renal disease and dialysis.

Johnson TA et al.

Human Molecular Genetics, 2023

35981075 (PubMed )
Supplement: johnsonta_tables2_ddac180.xlsx › III_TG_Driver_summary

Systematic assessment and optimizing algorithm of tumor mutational burden calculation and their implications in clinical decision-making.

Sun D et al.

Frontiers in Oncology, 2022

36425562 (PubMed )
Supplement: Table_3.xlsx › Sheet1

A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.

Kang T et al.

Breast Cancer Research : Bcr, 2020

32736587 (PubMed )
Supplement: 13058_2020_1322_MOESM3_ESM.xlsx › P_batch

Exome sequencing identifies somatic mutations in novel driver genes in non-small cell lung cancer.

Zhang M et al.

Aging, 2020

32629428 (PubMed )
Supplement: aging-12-103500-s002..xlsx › Sheet1

Loss-of-function mutations in KEAP1 drive lung cancer progression via KEAP1/NRF2 pathway activation.

Gong M et al.

Cell Communication and Signaling : Ccs, 2020

Fluorouracil sensitivity in a head and neck squamous cell carcinoma with a somatic DPYD structural variant.

Majounie E et al.

Cold Spring Harbor Molecular Case Studies, 2020

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Torrente L et al.

Redox Biology, 2020

32007910 (PubMed )
Supplement: mmc2.xlsx › Table_1_LuSCC

Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer.

Yu XJ et al.

Ebiomedicine, 2015

26288819 (PubMed )
Supplement: mmc6.xlsx › Sheet1

Somatic mutations of the KEAP1 gene in common solid cancers.

Yoo NJ et al.

Histopathology, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."