Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.C226S
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KEAP1

NM_203500.2:p.C226S

Associated Papers

S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling.

Ko Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production.

Cvetko F et al.

The Journal of Biological Chemistry, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."