Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.G186R
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KEAP1

NM_203500.2:p.G186R

Associated Papers

Regulation of Cell Proliferation and Nrf2-Mediated Antioxidant Defense: Conservation of Keap1 Cysteines and Nrf2 Binding Site in the Context of the Evolution of KLHL Family.

Shilovsky GA et al.

Life (basel, Switzerland), 2023

Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity.

Hong TH et al.

Journal for Immunotherapy of Cancer, 2020

33077514 (PubMed )
Supplement: jitc-2020-001199supp002.pdf

p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.

Cloer EW et al.

Molecular and Cellular Biology, 2018

Genetic changes of non-small cell lung cancer under neoadjuvant therapy.

Warth A et al.

Oncotarget, 2016

27105513 (PubMed )
Supplement: oncotarget-07-29761-s002.xlsx › Tabelle1

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.

Hast BE et al.

Cancer Research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."