Varaico: Literature-Extracted Genetic Variants

Gene:KEAP1
Variant:p.E117K
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KEAP1

NM_203500.2:p.E117K

Associated Papers

The Mutational Landscape of Cancer's Vulnerability to Ionizing Radiation.

Gopal P et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2022

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

NRF2-Driven KEAP1 Transcription in Human Lung Cancer.

Tian Y et al.

Molecular Cancer Research : Mcr, 2020

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Torrente L et al.

Redox Biology, 2020

32007910 (PubMed )
Supplement: mmc2.xlsx › Table_1_LuSCC

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells.

Testa U et al.

Cancers, 2018

30060526 (PubMed )
Supplement: cancers-10-00248-s001.docx

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Berger AH et al.

Cancer Cell, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."