Varaico: Literature-Extracted Genetic Variants

Gene:KHDRBS1
Variant:p.F118I
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KHDRBS1

NM_006559.3:p.F118I

Associated Papers

KEAP1 retention in phase-separated p62 bodies drives liver damage under autophagy-deficient conditions.

Takada S et al.

Embo Reports, 2025

Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

Ichimura Y et al.

Molecular Cell, 2013

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.

Komatsu M et al.

Nature Cell Biology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."