Varaico: Literature-Extracted Genetic Variants

Gene:KIF2C
Variant:p.G495A
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KIF2C

NM_006845.4:p.G495A

Associated Papers

The MLL/WDR5 complex promotes midbody recruitment of KIF2C for microtubule depolymerization and furrow initiation during cytokinesis.

Kataria A et al.

Journal of Cell Science, 2025

KIF2C condensation concentrates PLK1 and phosphorylated BRCA2 on kinetochore microtubules in mitosis.

Skobelkina A et al.

Nucleic Acids Research, 2025

KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization.

Zheng R et al.

Elife, 2022

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair.

Zhu S et al.

Elife, 2020

Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization.

Wang W et al.

The Journal of Biological Chemistry, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."