Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.C12Y
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KIT

NM_000222.3:p.C12Y

Associated Papers

Profiling of HER2, KRAS, and PIK3CA mutations in uterine cervical neuroendocrine carcinoma and implications for oncogenic driver targeting therapy.

Chao WR et al.

Cancer Genetics, 2025

Longitudinal ultra-sensitive mutation burden sequencing for precise minimal residual disease assessment in AML.

Wu Y et al.

Nature Communications, 2024

39543210 (PubMed )
Supplement: 41467_2024_54254_MOESM4_ESM.xlsx › No.11

Identification of genomic regions associated with differences in fleece type in Huacaya and Suri alpacas (Vicugna pacos).

Tan K et al.

Animal Genetics, 2024

Whole-genome sequencing of alpaca revealed variants in KIT gene potentially associated with the white coat phenotype.

Pallotti S et al.

Animal Genetics, 2023

Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.

Matrai CE et al.

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, 2022

Broad spectrum of regorafenib activity on mutant KIT and absence of clonal selection in gastrointestinal stromal tumor (GIST): correlative analysis from the GRID trial.

Jeffers M et al.

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2022

35050442 (PubMed )
Supplement: 10120_2021_1274_MOESM1_ESM.docx

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Papillary renal neoplasm with reverse polarity: A clinicopathological and molecular genetic characterization of 16 cases with expanding the morphologic spectrum and further support for a novel entity.

Shen M et al.

Frontiers in Oncology, 2022

Development and Validation of Targeted Gene Sequencing Panel Based Companion Diagnostic for Korean Patients with Solid Tumors.

Min BJ et al.

Cancers, 2021

c-KIT Analysis and Targeted Molecular Sequencing of Mesonephric Carcinomas of the Female Genital Tract.

Pors J et al.

The American Journal of Surgical Pathology, 2020

A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.

Windon AL et al.

Journal of Gastrointestinal Oncology, 2018

Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer.

Adamo P et al.

Oncotarget, 2017

Mutational profiling of acral melanomas in Korean populations.

Shim JH et al.

Experimental Dermatology, 2017

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Emelyanova M et al.

Oncotarget, 2017

28881731 (PubMed )
Supplement: oncotarget-08-52304-s002.xlsx › Sheet1

Somatic Mutations in Prostate Cancer: Closer to Personalized Medicine.

Alvarez-Cubero MJ et al.

Molecular Diagnosis & Therapy, 2017

COSMIC: High-Resolution Cancer Genetics Using the Catalogue of Somatic Mutations in Cancer.

Forbes SA et al.

Current Protocols in Human Genetics, 2016

Low prevalence of K-RAS, EGF-R and BRAF mutations in sinonasal adenocarcinomas. Implications for anti-EGFR treatments.

Franchi A et al.

Pathology Oncology Research : Por, 2014

A landscape of driver mutations in melanoma.

Hodis E et al.

Cell, 2012

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials.

Lovly CM et al.

Plos One, 2012

KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.

Tie J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

21239505 (PubMed )
Supplement: 10780432ccr101720-sup-supplementary_tables_s1-s4.pdf

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.

Krypuy M et al.

Bmc Cancer, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."